TAK-659 hydrochloride
Product Specifications
CAS Number
1952251-28-3
Target
VEGFR, FLT, JAK, Tyrosine Kinases, Syk
Related Pathways
JAK/STAT signaling, Stem Cells, Tyrosine Kinase/Adaptors, Angiogenesis, Chromatin/Epigenetic
Purity
0.9982
Bioactivity
TAK-659 hydrochloride (TAK-659) is a potent and selective inhibitor of spleen tyrosine kinase (SYK) with an IC50 value of 3.2 nM. It is selective against most other kinases, but potent toward both SYK and FLT3.
Smiles
Cl.Cn1cc(cn1)-c1nc(N[C@@H]2CCCC[C@@H]2N)c(F)c2CNC(=O)c12
Molecular Formula
C17H22ClFN6O
Molecular Weight
380.85
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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