E6446
Product Specifications
CAS Number
1219925-73-1
Target
TLR, Stearoyl-CoA Desaturase (SCD)
Related Pathways
Immunology/Inflammation, Metabolism
Purity
0.9999
Bioactivity
E6446 inhibits Toll-like receptor (TLR) 7 and 9 signaling. E6446 works in a variety of human and mouse cell types and inhibits DNA-TLR9 interaction in vitro. When administered to mice, this compound suppress responses to challenge doses of cytidine-phosphate-guanidine (CpG) -containing DNA, which stimulates TLR9.
Smiles
O(CCCN1CCCC1)C=2C=C3C(N=C(O3)C4=CC=C(OCCCN5CCCC5)C=C4)=CC2
Molecular Formula
C27H35N3O3
Molecular Weight
449.59
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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