What is the catalog number for OTS514?

The catalog number for OTS514 is T4134L.

What sizes are available for OTS514?

OTS514 is available in the following size(s): 1 mg, 5 mg, 1 mL - 10 mM (in DMSO), 10 mg, 25 mg, 50 mg, 100 mg, 200 mg.

How many pack sizes does OTS514 come in?

OTS514 is available in 8 different pack sizes.

OTS514 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures OTS514?

OTS514 is manufactured by Molfinity.

What is the estimated delivery time for OTS514?

Estimated delivery time for OTS514 is approximately 10 business day(s), depending on your location.

OTS514

Product Specifications

CAS Number

1338540-63-8

Target

Apoptosis, TOPK

Related Pathways

Apoptosis, MAPK

Purity

0.9962

Bioactivity

OTS514 (OTS514 Hydrochloride) is a potent TOPK inhibitor. OTS514 exhibits a growth-suppressive effect on small cell lung cancer. OTS514 effectively suppressed the growth of SCLC cell lines (IC50: 0.4 ~ 42.6 nM) . Treatment with OTS514 suppressed forkhead box protein M1 (FOXM1) activity. OTS514 treatment reduced CD90-positive SCLC cells and showed a higher cytotoxic effect against lung sphere-derived CSC-like SCLC cells.