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Obatoclax

Product Specifications

CAS Number

803712-67-6

Target

Parasite, Autophagy, Bcl-2 Family, Others

Related Pathways

Microbiology/Virology, Autophagy, Others, Apoptosis

Purity

0.9944

Bioactivity

Obatoclax (GX15-070), a pan-BCL-2 family proteins inhibitor and BH3 mimetic, exhibits a binding affinity (K_i) of 220 nM for BCL-2. It promotes autophagy-dependent cell death and cyclin D1 degradation via the proteasome. Additionally, Obatoclax demonstrates anti-cancer properties and broad-spectrum antiparasitic activity.

Smiles

C(=C1N=C(C=C1OC)C2=CC=3C(N2)=CC=CC3)C4=C(C)C=C(C)N4

Molecular Formula

C20H19N3O

Molecular Weight

317.38

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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