Obatoclax
Product Specifications
CAS Number
803712-67-6
Target
Parasite|||Autophagy|||Bcl-2 Family|||Others
Related Pathways
Microbiology/Virology|||Autophagy|||Others|||Apoptosis
Purity
0.9944
Bioactivity
Obatoclax (GX15-070), a pan-BCL-2 family proteins inhibitor and BH3 mimetic, exhibits a binding affinity (K_i) of 220 nM for BCL-2. It promotes autophagy-dependent cell death and cyclin D1 degradation via the proteasome. Additionally, Obatoclax demonstrates anti-cancer properties and broad-spectrum antiparasitic activity.
Smiles
C(=C1N=C(C=C1OC)C2=CC=3C(N2)=CC=CC3)C4=C(C)C=C(C)N4
Molecular Formula
C20H19N3O
Molecular Weight
317.38
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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