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PF-04753299

Product Specifications

CAS Number

1289620-49-0

Target

Others, Antibacterial

Related Pathways

Others, Microbiology/Virology

Purity

0.9988

Bioactivity

PF-04753299 is a potent and selective inhibitor of UDP-3-O- (R-3-hydroxymyristol) -N-acetylglucosamine deacetylase (LpxC), demonstrating bactericidal effects against gonococcal isolates and exhibiting inhibitory activity against E. coli, P. aeruginosa, and K. pneumoniae, with minimum inhibitory concentration (MIC) 90 values of 2 μg/ml, 4 μg/ml, and 16 μg/ml, respectively. This compound is utilized in researching gram-negative bacterial infections [1].

Smiles

C(C[C@](C(NO)=O)(S(C)(=O)=O)C)C1=CC=C(C=C1)C2=CC=CC=C2

Molecular Formula

C18H21NO4S

Molecular Weight

347.43

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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