PF-04753299
Product Specifications
CAS Number
1289620-49-0
Target
Others, Antibacterial
Related Pathways
Others, Microbiology/Virology
Purity
0.9988
Bioactivity
PF-04753299 is a potent and selective inhibitor of UDP-3-O- (R-3-hydroxymyristol) -N-acetylglucosamine deacetylase (LpxC), demonstrating bactericidal effects against gonococcal isolates and exhibiting inhibitory activity against E. coli, P. aeruginosa, and K. pneumoniae, with minimum inhibitory concentration (MIC) 90 values of 2 μg/ml, 4 μg/ml, and 16 μg/ml, respectively. This compound is utilized in researching gram-negative bacterial infections [1].
Smiles
C(C[C@](C(NO)=O)(S(C)(=O)=O)C)C1=CC=C(C=C1)C2=CC=CC=C2
Molecular Formula
C18H21NO4S
Molecular Weight
347.43
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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