SP-96
Product Specifications
CAS Number
2682114-54-9
Target
Aurora Kinase
Related Pathways
Cell Cycle/Checkpoint, Chromatin/Epigenetic
Purity
0.9954
Bioactivity
SP-96 is a highly effective and selective inhibitor of Aurora B with an IC50 of 0.316 nM. SP-96 shows selective growth inhibition in NCI60 screening, including MDA-MD-468 (GI50=107 nM) . SP-96 can be used in triple negative breast cancer studies.
Smiles
Cn1cc(cn1)-c1ccc2c(Nc3cccc(NC(=O)Nc4cccc(F)c4)c3)ncnc2c1
Molecular Formula
C25H20FN7O
Molecular Weight
453.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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