CAM 833
Product Specifications
CAS Number
2758364-02-0
Target
DNA/RNA Synthesis, Cell Cycle Arrest, Apoptosis
Related Pathways
Cell Cycle/Checkpoint, Apoptosis, DNA Damage/DNA Repair
Purity
0.9983
Bioactivity
CAM 833 is an effective orthosteric inhibitor of the BRCA2-RAD51 interaction, inhibiting RAD51 aggregation, enhancing DNA damage-induced apoptosis, increasing 4N cell cycle arrest, and disrupting homologous DNA repair (HDR), and can be used for cancer therapy.
Smiles
C(N[C@@H](C)C1=C(Cl)C=C(OC)C=C1)(=O)[C@H]2N(C(CNC(=O)C3=NC4=C(C=C3)C=C(F)C=C4)=O)C[C@H](O)C2
Molecular Formula
C26H26ClFN4O5
Molecular Weight
528.96
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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