PARPYnD
Product Specifications
CAS Number
2561483-27-8
Target
Others, PARP
Related Pathways
Others, Chromatin/Epigenetic, DNA Damage/DNA Repair
Bioactivity
PARPYnD is a potent photoaffinity probe for poly (ADP-ribose) polymerase (PARP) (IC50 values for PARP2, PARP1 and PARP6 are 6, 38 and 230 nM, respectively) . PARPYnD labels PARP1 and PARP2 in the cell when an N3 functionalized fluorescent probe is attached and can inhibit isolated PARP6.
Smiles
C(CC(NC=1C=C(C#N)C(=NC1)N2CCN(C(=O)C3=CC(CC=4C=5C(C(=O)NN4)=CC=CC5)=CC=C3)CC2)=O)C6(CCC#C)N=N6
Molecular Formula
C34H31N9O3
Molecular Weight
613.67
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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