OB 24 hydrochloride
Product Specifications
CAS Number
939825-12-4
Target
ROS, Others
Related Pathways
Others, Immunology/Inflammation
Bioactivity
OB 24 hydrochloride is a potent and selective heme oxygenase 1 (HO-1) inhibitor (IC50 values are 1.9 and >100 μM for HO-1 and HO-2 respectively), reduces protein carbonylation and reactive oxygen species formation in advanced prostate cancer cells (PCA) . Inhibits cell proliferationin vitroand PCA tumor growth and lymph node/lung metastasesin vivo. Synergizes with Taxol.
Smiles
Cl.Brc1ccc(CCC2(Cn3ccnc3)OCCO2)cc1
Molecular Formula
C15H18BrClN2O2
Molecular Weight
373.68
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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