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OB 24 hydrochloride

Product Specifications

CAS Number

939825-12-4

Target

ROS|||Others

Related Pathways

Others|||Immunology/Inflammation

Bioactivity

OB 24 hydrochloride is a potent and selective heme oxygenase 1 (HO-1) inhibitor (IC50 values are 1.9 and >100 ?M for HO-1 and HO-2 respectively), reduces protein carbonylation and reactive oxygen species formation in advanced prostate cancer cells (PCA) . Inhibits cell proliferationin vitroand PCA tumor growth and lymph node/lung metastasesin vivo. Synergizes with Taxol.

Smiles

Cl.Brc1ccc(CCC2(Cn3ccnc3)OCCO2)cc1

Molecular Formula

C15H18BrClN2O2

Molecular Weight

373.68

Shipping Conditions

Cool pack

Storage Temperature

-20°C

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