DMT-2'-OMe-Bz-C
DMT-2'-OMe-Bz-C is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].
Product Specifications
CAS Number
110764-74-4
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Nucleoside Antimetabolite/Analog
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dmt-2-ome-bz-c.html
Concentration
10mM
Purity
99.52
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O[C@H]1[C@@H](OC)[C@H](N2C(N=C(NC(C3=CC=CC=C3)=O)C=C2)=O)O[C@@H]1COC(C4=CC=C(OC)C=C4)(C5=CC=C(OC)C=C5)C6=CC=CC=C6
Molecular Formula
C38H37N3O8
Molecular Weight
663.72
Precautions
H315, H319, H335
References & Citations
[1]Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3 (11) :1062-8.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
PKSH031546 50 µg
Recombinant Human PAPPA2/Pappalysin 2 Protein (His Tag)
Sign In for Pricing
View Details 