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MS 154N

Product Specifications

CAS Number

2675490-97-6

Target

Others|||PROTACs|||EGFR

Related Pathways

PROTAC|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors|||Others|||Angiogenesis

Bioactivity

MS 154N is a negative control for MS 154. The compound exhibits high binding-affinity for WT and L858R-mutant EGFR (Kdvalues are 3 and 4.3 nM, respectively), but does not significantly induce degradation of EGFR mutants.

Smiles

O=C1C=2C(C(=O)N1C3C(=O)N(C)C(=O)CC3)=CC=CC2OCCCCCCCCNC(CCN4CCN(CCCOC5=CC6=C(C=C5OC)N=CN=C6NC7=CC(Cl)=C(F)C=C7)CC4)=O

Molecular Formula

C47H56ClFN8O8

Molecular Weight

915.45

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Product Datasheet

https://www.targetmol.com/attachment/DataSheet/EF4B548C-A4CE-490E-9890-0A638CC7E38A/T41157

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