EMD 527040 hydrochloride
Product Specifications
CAS Number
2758431-92-2
Target
Others
Related Pathways
Others
Bioactivity
EMD 527040 hydrochloride is an effective integrin αVβ6 inhibitor. The IC 50 values of EMD 527040 hydrochloride were 6 nM and 1.6 μM to inhibit αVβ6 binding to fibronectin and αVβ6 expression cells to fibronectin, respectively. EMD 527040 hydrochloride shows antifibrotic activity in animal models of biliary fibrosis and is active in vivo.
Smiles
O=C(CCCCNC1=CC=CC=N1)N[C@@H](COCC2=CC=CC=C2)C(NC(C3=CC(Cl)=CC(Cl)=C3)CC(O)=O)=O.Cl
Molecular Formula
C29H33Cl3N4O5
Molecular Weight
623.96
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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