Auraptene
Product Specifications
CAS Number
495-02-3
Target
PPAR, MMP, BACE, Antibacterial
Related Pathways
DNA Damage/DNA Repair, Microbiology/Virology, Metabolism, Proteases/Proteasome, Neuroscience
Purity
>99.99%
Bioactivity
Auraptene is a coumarin derived from citrus plants that bears a geranyloxyl moiety at its C-7. It has anti-inflammatory, anti-carcinogenic, anti-bacterial, neuroprotective, and hepatoprotective activities. It inhibits leukocyte activation and induces phase II enzymes during the initiation phase of carcinogenesis.1 When examined for its potential use in Alzheimer's disease treatment, auraptene was shown to inhibit β-secretase (BACE1) activity with an IC50 value of 345.1 μM.
Smiles
CC(C)=CCCC(C)=CCOc1ccc2ccc(=O)oc2c1
Molecular Formula
C19H22O3
Molecular Weight
298.38
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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