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Auraptene

Product Specifications

CAS Number

495-02-3

Target

PPAR, MMP, BACE, Antibacterial

Related Pathways

DNA Damage/DNA Repair, Microbiology/Virology, Metabolism, Proteases/Proteasome, Neuroscience

Purity

>99.99%

Bioactivity

Auraptene is a coumarin derived from citrus plants that bears a geranyloxyl moiety at its C-7. It has anti-inflammatory, anti-carcinogenic, anti-bacterial, neuroprotective, and hepatoprotective activities. It inhibits leukocyte activation and induces phase II enzymes during the initiation phase of carcinogenesis.1 When examined for its potential use in Alzheimer's disease treatment, auraptene was shown to inhibit β-secretase (BACE1) activity with an IC50 value of 345.1 μM.

Smiles

CC(C)=CCCC(C)=CCOc1ccc2ccc(=O)oc2c1

Molecular Formula

C19H22O3

Molecular Weight

298.38

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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