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EFdA-TP

Product Specifications

CAS Number

950913-56-1

Target

Reverse Transcriptase|||HIV Protease|||Others|||DNA/RNA Synthesis

Related Pathways

Proteases/Proteasome|||Cell Cycle/Checkpoint|||Microbiology/Virology|||DNA Damage/DNA Repair|||Others

Bioactivity

EFdA-TP, a highly potent nucleoside reverse transcriptase (RT) inhibitor, exerts its inhibitory effect on RT-catalyzed DNA synthesis through both immediate and delayed chain termination mechanisms, commonly referred to as ICT and DCT, respectively. Additionally, EFdA-TP demonstrates its efficacy in inhibiting HIV-1 RT through multiple pathways.

Smiles

Nc1nc(F)nc2n(cnc12)[C@H]1C[C@H](O)[C@@](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)(O1)C#C

Molecular Formula

C12H15FN5O12P3

Molecular Weight

533.195

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Product Datasheet

https://www.targetmol.com/attachment/DataSheet/8FCC39CE-256E-4E20-A9A3-09F6E0BA7BB5/T41110

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