EFdA-TP
Product Specifications
CAS Number
950913-56-1
Target
Reverse Transcriptase|||HIV Protease|||Others|||DNA/RNA Synthesis
Related Pathways
Proteases/Proteasome|||Cell Cycle/Checkpoint|||Microbiology/Virology|||DNA Damage/DNA Repair|||Others
Bioactivity
EFdA-TP, a highly potent nucleoside reverse transcriptase (RT) inhibitor, exerts its inhibitory effect on RT-catalyzed DNA synthesis through both immediate and delayed chain termination mechanisms, commonly referred to as ICT and DCT, respectively. Additionally, EFdA-TP demonstrates its efficacy in inhibiting HIV-1 RT through multiple pathways.
Smiles
Nc1nc(F)nc2n(cnc12)[C@H]1C[C@H](O)[C@@](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)(O1)C#C
Molecular Formula
C12H15FN5O12P3
Molecular Weight
533.195
Shipping Conditions
Cool pack
Storage Temperature
-20°C
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