JTS-653
Product Specifications
CAS Number
942614-99-5
Target
Others|||TRP/TRPV Channel
Related Pathways
Others|||Membrane transporter/Ion channel
Bioactivity
JTS-653 is a potent and selective in vitro and in vivo antagonist of transient receptor potential vanilloid 1 (TRPV1) . It effectively attenuates chronic pain resistant to non-steroidal anti-inflammatory drugs.
Smiles
Cc1ccc(nc1)N1[C@@H](CO)COc2c1cccc2C(=O)Nc1ccc(OCC(F)(F)F)nc1
Molecular Formula
C23H21F3N4O4
Molecular Weight
474.44
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Curated Selection
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