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MK-8617

Product Specifications

CAS Number

1187990-87-9

Target

HIF/HIF Prolyl-Hydroxylase

Related Pathways

Chromatin/Epigenetic, Metabolism

Purity

>99.99%

Bioactivity

MK-8617 is an orally available HIF PHD1 3 pan-inhibitor, inhibiting PHD1/2/3 (IC50: 1.0/1.0/14 nM) .

Smiles

COc1ccc(cc1)C(NC(=O)c1cnc([nH]c1=O)-c1cccnn1)c1ccc(OC)cc1

Molecular Formula

C24H21N5O4

Molecular Weight

443.45

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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