NMDA receptor antagonist 2
Product Specifications
CAS Number
875898-41-2
Target
Others, iGluR
Related Pathways
Neuroscience, Membrane transporter/Ion channel, Others
Bioactivity
NMDA receptor antagonist 2 is a highly potent and orally active NR2B subtype-selective antagonist of the N-methyl-D-aspartate (NMDA) receptor, with an IC50 of 1.0 nM and a Ki value of 0.88 nM. This compound is valuable in scientific investigations of neuropathic pain and Parkinson's disease.
Smiles
Cc1ccc(Cc2noc(n2)[C@H]2CC[C@@H](C2)Nc2ncnc3[nH]ncc23)cc1
Molecular Formula
C20H21N7O
Molecular Weight
375.436
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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