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NMDA receptor antagonist 2

Product Specifications

CAS Number

875898-41-2

Target

Others|||iGluR

Related Pathways

Neuroscience|||Membrane transporter/Ion channel|||Others

Bioactivity

NMDA receptor antagonist 2 is a highly potent and orally active NR2B subtype-selective antagonist of the N-methyl-D-aspartate (NMDA) receptor, with an IC50 of 1.0 nM and a Ki value of 0.88 nM. This compound is valuable in scientific investigations of neuropathic pain and Parkinson's disease.

Smiles

Cc1ccc(Cc2noc(n2)[C@H]2CC[C@@H](C2)Nc2ncnc3[nH]ncc23)cc1

Molecular Formula

C20H21N7O

Molecular Weight

375.436

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Product Datasheet

https://www.targetmol.com/attachment/DataSheet/D78832EA-1576-463B-AE70-D0C2A8A7779C/T40999

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