What is the catalog number for AG126?

The catalog number for AG126 is T4092.

What sizes are available for AG126?

AG126 is available in the following size(s): 5 mg, 1 mL - 10 mM (in DMSO), 10 mg, 25 mg, 50 mg, 100 mg, 200 mg.

How many pack sizes does AG126 come in?

AG126 is available in 7 different pack sizes.

AG126 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures AG126?

AG126 is manufactured by Molfinity.

What is the estimated delivery time for AG126?

Estimated delivery time for AG126 is approximately 10 business day(s), depending on your location.

AG126

Product Specifications

CAS Number

118409-62-4

Target

COX, ERK

Related Pathways

Immunology/Inflammation, MAPK, Neuroscience

Purity

0.9872

Bioactivity

AG126 (Tyrphostin AG126) selectively inhibits the phosphorylation of ERK1 (p44) and ERK2 (p42) at 25-50 μM. It blocks the production of TNF-α in vitro2 and in vivo, attenuating signaling through NF-κB, the induced expression of COX-2 and iNOS, and the inflammatory response in diverse animal models. AG-126 weakly inhibits epidermal GFRK (IC50: 450 μM) and platelet-derived GFRK (IC50 > 100 μM) .