Rachelmycin
Product Specifications
CAS Number
69866-21-3
Target
DNA/RNA Synthesis, Others, Antibiotic
Related Pathways
Cell Cycle/Checkpoint, DNA Damage/DNA Repair, Others, Microbiology/Virology
Bioactivity
Rachelmycin (CC-1065; NSC 298223) is a potent naturally antibiotic isolated from Streptomyces zelensis . Rachelmycin binds non-covalently and covalently (N-3 adenine adduct) in the minor groove of B-form DNA. Rachelmycin has exceptionally potent antitumor activity.
Smiles
[H][C@]12C[C@@]11C(=CC(=O)c3[nH]cc(C)c13)N(C2)C(=O)c1cc2c3CCN(C(=O)c4cc5c6CCN(C(N)=O)c6c(O)c(OC)c5[nH]4)c3c(O)c(OC)c2[nH]1 |c:5|
Molecular Formula
C37H33N7O8
Molecular Weight
703.712
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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