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LY-294002 hydrochloride

Product Specifications

CAS Number

934389-88-5

Target

PI3K, Apoptosis, Casein Kinase, DNA-PK

Related Pathways

PI3K/Akt/mTOR signaling, DNA Damage/DNA Repair, Apoptosis, Metabolism, Stem Cells

Purity

0.9998

Bioactivity

LY-294002 hydrochloride (NSC 697286) is a synthetic molecule inhibitor of PI3Kα/δ/β (IC50: 0.5/0.57/0.97 μM, in cell-free assays) ; more stable than Wortmannin in solution, and also is a blocker of autophagosome formation.

Smiles

Cl.O=c1cc(oc2c(cccc12)-c1ccccc1)N1CCOCC1

Molecular Formula

C19H17NO3·HCl

Molecular Weight

343.81

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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