12,14-Dichlorodehydroabietic acid
Product Specifications
CAS Number
65281-77-8
Target
Others|||GABA Receptor|||Potassium Channel
Related Pathways
Others|||Neuroscience|||Membrane transporter/Ion channel
Bioactivity
12,14-Dichlorodehydroabietic acid, a chlorinated resin acid, exhibits potent calcium-activated potassium (BK) channel opening activity, effectively inhibits GABA-dependent chloride influx in the mammalian brain as a non-competitive antagonist of GABA A receptors, induces elevation in cytosolic free calcium levels, and promotes neurotransmitter release.
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[H][C@@]12CCc3c(Cl)c(C(C)C)c(Cl)cc3[C@@]1(C)CCC[C@@]2(C)C(O)=O
Molecular Formula
C20H26Cl2O2
Molecular Weight
369.33
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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