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GSK 872 hydrochloride

Product Specifications

CAS Number

2703752-81-0

Target

RIP kinase

Related Pathways

NF-κB, Apoptosis

Purity

0.9982

Bioactivity

GSK872 HCl (1346546-69-7 free base) (GSK2399872A) is an effective and specific RIP3 kinase inhibitor. It binds RIP3 kinase domain with high affinity (IC50: 1.8 nM) and inhibits kinase activity (IC50: 1.3 nM) .

Smiles

Cl.CC(C)S(=O)(=O)c1ccc2nccc(Nc3ccc4scnc4c3)c2c1

Molecular Formula

C19H18ClN3O2S2

Molecular Weight

419.94

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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