GSK 872 hydrochloride
Product Specifications
CAS Number
2703752-81-0
Target
RIP kinase
Related Pathways
NF-κB, Apoptosis
Purity
0.9982
Bioactivity
GSK872 HCl (1346546-69-7 free base) (GSK2399872A) is an effective and specific RIP3 kinase inhibitor. It binds RIP3 kinase domain with high affinity (IC50: 1.8 nM) and inhibits kinase activity (IC50: 1.3 nM) .
Smiles
Cl.CC(C)S(=O)(=O)c1ccc2nccc(Nc3ccc4scnc4c3)c2c1
Molecular Formula
C19H18ClN3O2S2
Molecular Weight
419.94
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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