GSK-872
Product Specifications
CAS Number
1346546-69-7
Target
RIP kinase
Related Pathways
Apoptosis|||NF-?B
Purity
>99.99%
Bioactivity
GSK-872 (GSK2399872A) is an effective and specific RIP3 kinase inhibitor. It binds RIP3 kinase domain with high affinity (IC50: 1.8 nM) and inhibits kinase activity (IC50: 1.3 nM) .
Smiles
CC(C)S(=O)(=O)c1ccc2nccc(Nc3ccc4scnc4c3)c2c1
Molecular Formula
C19H17N3O2S2
Molecular Weight
383.49
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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