GSK-872

Product Specifications

CAS Number

1346546-69-7

Target

RIP kinase

Related Pathways

Apoptosis|||NF-?B

Purity

>99.99%

Bioactivity

GSK-872 (GSK2399872A) is an effective and specific RIP3 kinase inhibitor. It binds RIP3 kinase domain with high affinity (IC50: 1.8 nM) and inhibits kinase activity (IC50: 1.3 nM) .

Smiles

CC(C)S(=O)(=O)c1ccc2nccc(Nc3ccc4scnc4c3)c2c1

Molecular Formula

C19H17N3O2S2

Molecular Weight

383.49

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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