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E6446 dihydrochloride

Product Specifications

CAS Number

1345675-25-3

Target

Stearoyl-CoA Desaturase (SCD), TLR

Related Pathways

Metabolism, Immunology/Inflammation

Purity

0.9944

Bioactivity

E6446 dihydrochloride is a novel synthetic antagonist for nucleic acid-sensing TLRs; potently suppressed DNA stimulation of HEK:TLR9 cells with IC50 of 10 nM.

Smiles

Cl.Cl.C(COc1ccc(cc1)-c1nc2ccc(OCCCN3CCCC3)cc2o1)CN1CCCC1

Molecular Formula

C27H37Cl2N3O3

Molecular Weight

522.51

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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