Meclizine
Product Specifications
CAS Number
569-65-3
Target
Apoptosis, Histamine Receptor
Related Pathways
GPCR/G Protein, Apoptosis, Immunology/Inflammation, Neuroscience
Purity
0.9955
Bioactivity
Meclizine, also known as Meclozine, is a piperazine class H1 antagonist with antihistamine properties that inhibits the interaction of histamine at H1 receptors reversibly. It serves as an effective anti-motion sickness agent, able to cross the blood-brain barrier. Additionally, Meclizine acts as an agonist ligand for the mouse constitutive androstane receptor (CAR) and an inverse agonist for human CAR, making it useful in research on polyQ toxicity disorders, including Huntington's disease.
Smiles
Cc1cccc(CN2CCN(CC2)C(c2ccccc2)c2ccc(Cl)cc2)c1
Molecular Formula
C25H27ClN2
Molecular Weight
390.95
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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