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CAY10602

Product Specifications

CAS Number

374922-43-7

Target

Sirtuin

Related Pathways

DNA Damage/DNA Repair, Chromatin/Epigenetic

Purity

>99.99%

Bioactivity

CAY10602 is a SIRT1 activator derived from high throughput screening for compounds that enhance SIRT1-mediated deacetylation of a SIRT1-specific substrate. Functional assays indicate that CAY10602 dose-dependently suppresses NF-κB-dependent induction of TNF-α by lipopolysaccharide in THP-1 cells, achieving approximately 75% inhibition at 60 μM without cytotoxicity.

Smiles

Nc1c(c2nc3ccccc3nc2n1-c1ccc(F)cc1)S(=O)(=O)c1ccccc1

Molecular Formula

C22H15FN4O2S

Molecular Weight

418.44

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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