Cpd27
Product Specifications
CAS Number
501693-48-7
Target
RIP kinase, Tie-2, VEGFR
Related Pathways
Apoptosis, Tyrosine Kinase/Adaptors, Angiogenesis, NF-κB
Purity
0.9889
Bioactivity
Cpd27 (TIE-2/VEGFR-2 kinase-IN-2) is a TIE-2 and VEGFR-2 inhibitor that inhibits RIPK1 and protects RGCs from TNF-stimulated cell death and can be used to study glaucoma.
Smiles
O=C(NC=1C=CC(=CC1)C2=COC3=NC=NC(N)=C32)NC4=CC(=CC=C4F)C(F)(F)F
Molecular Formula
C20H13F4N5O2
Molecular Weight
431.34
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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