Thiophene-2
Product Specifications
CAS Number
420089-51-6
Target
Others, Antibacterial
Related Pathways
Microbiology/Virology, Others
Bioactivity
Thiophene-2 (TP2) is a targeted inhibitor of polyketide synthase 13 (Pks13), specifically designed to disrupt mycolic acid biosynthesis, effectively inducing rapid cell death in mycobacteria. It demonstrates notable anti-tuberculosis activity and exhibits a minimum inhibitory concentration (MIC) value of 1 μM against Mycobacterium tuberculosis.
Smiles
O=C(OC)C1=C(SC2=C1CCCCC2)NC(=O)C=3C(F)=C(F)C(F)=C(F)C3F
Molecular Formula
C18H14F5NO3S
Molecular Weight
419.37
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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