KML29
Product Specifications
CAS Number
1380424-42-9
Target
Lipase, MAGL
Related Pathways
Metabolism
Purity
0.9865
Bioactivity
KML29 is highly selective and effective monoacylglycerol lipase (MAGL) inhibitor. It has effective inhibition of human/mouse/rat MAGL (IC50: 5.9/15/43 nM) . It has not inhibitory for FAAH (IC50 > 50 μM) . It also effectively and selectively blocks hydrolysis of 2-arachidonoylglycerol (2-AG) in mice (IC50: 2.5 nM, 2-AG; >50 μM, AEA) .
Smiles
OC(C1CCN(CC1)C(=O)OC(C(F)(F)F)C(F)(F)F)(c1ccc2OCOc2c1)c1ccc2OCOc2c1
Molecular Formula
C24H21F6NO7
Molecular Weight
549.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS6168146-01 0.1 mL
TRAPPC4 (Trafficking Protein Particle Complex 4, CGI-104, HSPC172, PTD009, SBDN, SYNBINDIN, TRS23) (APC)
Sign In for Pricing
View Details MBS6168146-02 5x 0.1 mL
TRAPPC4 (Trafficking Protein Particle Complex 4, CGI-104, HSPC172, PTD009, SBDN, SYNBINDIN, TRS23) (APC)
Sign In for Pricing
View Details V8657-100UG 100 µg
Recombinant Type II Cytokeratin Antibody (CK1-8)
Sign In for Pricing
View Details 
042291-ML750 100 µL
SRC, NT (SRC, SRC1, Proto-oncogene tyrosine-protein kinase Src, Proto-oncogene c-Src, pp60c-src) (MaxLight 750) discontinued
Sign In for Pricing
View Details