KML29
Product Specifications
CAS Number
1380424-42-9
Target
Lipase, MAGL
Related Pathways
Metabolism
Purity
0.9865
Bioactivity
KML29 is highly selective and effective monoacylglycerol lipase (MAGL) inhibitor. It has effective inhibition of human/mouse/rat MAGL (IC50: 5.9/15/43 nM) . It has not inhibitory for FAAH (IC50 > 50 μM) . It also effectively and selectively blocks hydrolysis of 2-arachidonoylglycerol (2-AG) in mice (IC50: 2.5 nM, 2-AG; >50 μM, AEA) .
Smiles
OC(C1CCN(CC1)C(=O)OC(C(F)(F)F)C(F)(F)F)(c1ccc2OCOc2c1)c1ccc2OCOc2c1
Molecular Formula
C24H21F6NO7
Molecular Weight
549.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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