Melflufen hydrochloride
Product Specifications
CAS Number
380449-54-7
Target
Others, Apoptosis, DNA Alkylator/Crosslinker
Related Pathways
DNA Damage/DNA Repair, Others, Apoptosis
Bioactivity
Melflufen (Melphalan flufenamide) hydrochloride, an alkylating agent and dipeptide prodrug of Melphalan, exhibits antitumor activity by inducing irreversible DNA damage and cytotoxicity in multiple myeloma (MM) cells, while also inhibiting angiogenesis.
Smiles
Cl.CCOC(=O)[C@H](Cc1ccc(F)cc1)NC(=O)[C@@H](N)Cc1ccc(cc1)N(CCCl)CCCl
Molecular Formula
C24H31Cl3FN3O3
Molecular Weight
534.88
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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