Namoline
Product Specifications
CAS Number
342795-11-3
Target
Histone Demethylase, Others
Related Pathways
Others, Chromatin/Epigenetic
Bioactivity
Namoline is a γ-pyrone compound that functions as a selective and reversible inhibitor of Lysine-specific demethylase 1 (LSD1) with an IC50 of 51 μM in an HRP-coupled enzymatic assay. By impairing LSD1 demethylase activity, Namoline effectively inhibits cell proliferation. Due to its characteristics, Namoline holds promise for research pertaining to androgen-dependent prostate cancer.
Smiles
FC(F)(F)c1oc2ccc(cc2c(=O)c1Cl)N(=O)=O
Molecular Formula
C10H3ClF3NO4
Molecular Weight
293.58
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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