TTBK1-IN-1
Product Specifications
CAS Number
2735015-60-6
Target
Microtubule Associated
Related Pathways
Cytoskeletal Signaling
Bioactivity
TTBK1-IN-1 (compound 31) is a potent and selective tau microtubule protein kinase 1 (TTBK1) inhibitor (IC50=315 nM) with central nervous system (CNS) penetration that inhibits tau phosphorylation at the disease-associated Ser 422 epitope, and can be used to study Alzheimer's disease.
Smiles
C(#C[C@@](CC)(C)O)C=1C=C2N(C=CC2=CN1)C=3C=C(OC)N=C(N)N3
Molecular Formula
C18H19N5O2
Molecular Weight
337.38
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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