AV-153
Product Specifications
CAS Number
27296-05-5
Target
Others|||DNA/RNA Synthesis
Related Pathways
Others|||DNA Damage/DNA Repair|||Cell Cycle/Checkpoint
Bioactivity
AV-153 is a 1,4-dihydropyridine derivative with antimutagenic properties. It intercalates into DNA at single strand breaks, resulting in reduced DNA damage and stimulation of DNA repair in human cells in vitro. AV-153 also interacts with thymine and cytosine and influences poly (ADP) ribosylation. Moreover, AV-153 exhibits anti-cancer activity.
Smiles
[Na].CCOC(=O)C1=C(C)NC(C)=C(C1C(O)=O)C(=O)OCC|c:5,10|
Molecular Formula
C14H19NNaO6
Molecular Weight
320.297
Shipping Conditions
Cool pack
Storage Temperature
-20°C
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