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IRE1α kinase-IN-6

Product Specifications

CAS Number

2715123-88-7

Target

IRE1, Others

Related Pathways

Others, Cell Cycle/Checkpoint

Bioactivity

IRE1α kinase-IN-6 is a potent IRE1α inhibitor with an IC50 value of 4.4 nM.

Smiles

N[C@H]1CC[C@@H](CC1)Nc1ncnc2c(csc12)C(=O)Nc1c(Cl)ccc(NS(=O)(=O)c2ccccc2Cl)c1F |wU:4.7,wD:1.0,(-4,-5.39,;-2.67,-4.62,;-1.33,-5.39,;,-4.62,;,-3.08,;-1.33,-2.31,;-2.67,-3.08,;1.33,-2.31,;1.33,-.77,;2.67,,;2.67,1.54,;1.33,2.31,;,1.54,;-1.46,2.02,;-2.37,.77,;-1.46,-.48,;;-1.94,3.48,;-.91,4.63,;-3.45,3.8,;-3.92,5.27,;-2.89,6.41,;-1.39,6.09,;-3.37,7.87,;-4.87,8.19,;-5.91,7.05,;-7.41,7.37,;-7.89,8.83,;-9.35,8.36,;-6.42,9.31,;-8.36,10.3,;-7.33,11.44,;-7.81,12.91,;-9.31,13.23,;-10.35,12.08,;-9.87,10.62,;-10.9,9.48,;-5.43,5.59,;-6.46,4.44,)|

Molecular Formula

C25H23Cl2FN6O3S2

Molecular Weight

609.52

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Frequently Asked Questions

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