ITK/TRKA-IN-1
Product Specifications
CAS Number
2655557-54-1
Target
Others, Tyrosine Kinases
Related Pathways
Tyrosine Kinase/Adaptors, Others
Bioactivity
ITK/TRKA-IN-1 is a chemical compound that functions as a dual inhibitor of IL-2-inducible T-cell kinase (ITK) and tropomyosin receptor kinase A (TRKA) . With an IC50 value of 1.0 nM, it effectively inhibits ITK activity and demonstrates a remarkable 96% inhibition of TRKA.
Smiles
[H][C@]12Cc3c(C[C@@]1(C)C2(F)F)[nH]nc3-c1nc2cc(C)c(cc2[nH]1)N(C)C(=O)[C@H](C)N1CCOCC1
Molecular Formula
C25H30F2N6O2
Molecular Weight
484.552
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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