DSM705
Product Specifications
CAS Number
2653225-38-6
Target
Others, Parasite, Dehydrogenase
Related Pathways
Others, Metabolism, Microbiology/Virology
Bioactivity
DSM705 is a pyrrole-based inhibitor of Dihydroorotate Dehydrogenase (DHODH) . It demonstrates high potency in the nanomolar range against Plasmodium DHODH and Plasmodium parasites, while not interfering with mammalian DHODHs. DSM705 shows significant efficacy as an antimalarial compound.
Smiles
C[C@@H](NC(=O)c1[nH]cc(c1C)C1(CC1)c1ccc(nc1)C(F)(F)F)c1nnc[nH]1
Molecular Formula
C19H19F3N6O
Molecular Weight
404.397
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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