XVA143

Product Specifications

CAS Number

264275-77-6

Target

Integrin

Related Pathways

Cytoskeletal Signaling

Bioactivity

XVA143 is an integrin ?/? I-like allosteric antagonist that inhibits LFA-1 (?L?2 integrin) -dependent firm adhesion and induces an extended conformation of integrins.

Smiles

C(NCC1=CC(O)=CC=C1)(=O)C2=CC(Cl)=C(C(N[C@@H](CNC(=O)C3=CC(O)=CC(O)=C3)C(O)=O)=O)C(Cl)=C2

Molecular Formula

C25H21Cl2N3O8

Molecular Weight

562.36

Shipping Conditions

Cool pack

Storage Temperature

-20°C

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