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RM-018

Product Specifications

CAS Number

2641993-55-5

Target

Others, Kras, Ras

Related Pathways

Others, GPCR/G Protein, MAPK

Bioactivity

RM-018 is a powerful tricomplex inhibitor that specifically targets the active state of KRAS G12C. It exhibits unique functional characteristics and possesses the ability to bind and inhibit both KRAS G12C and KRAS G12C/Y96D, potentially overcoming resistance.

Smiles

CCn1c(c2CC(C)(C)COC(=O)[C@@H]3CCCN(N3)C(=O)[C@H](Cc3cccc(c3)-c3ccc1c2c3)NC(=O)[C@H](C(C)C)N(C)C(=O)[C@H]1CCN(C1)C(=O)C#CCN1CCOCC1)-c1cccnc1[C@H](C)OC

Molecular Formula

C56H72N8O8

Molecular Weight

985.24

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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