VCP/p97 inhibitor-1
Product Specifications
CAS Number
2630950-38-6
Target
Others|||p97
Related Pathways
Others|||Ubiquitination
Bioactivity
VCP/p97 inhibitor-1, a highly effective compound, inhibits VCP/p97 (also known as Cdc48, CDC-48, or Ter94) with an IC 50 of 54.7 nM. This inhibitor induces a disruption in protein homeostasis and interferes with the degradation process of misfolded polypeptides by the ubiquitin-proteasome system (UPS) .
Smiles
Cc1cc2c(NS(C)(=O)=O)cccc2n1-c1nc2CCCc2c(NCc2cccc(c2)B(O)O)n1
Molecular Formula
C24H26BN5O4S
Molecular Weight
491.37
Shipping Conditions
Cool pack
Storage Temperature
-20°C
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