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2',3'-cGAMP-C2-PPA

Product Specifications

CAS Number

2586047-11-0

Target

STING, Drug-Linker Conjugates for ADC

Related Pathways

Antibody-drug Conjugate/ADC Related, Immunology/Inflammation

Bioactivity

2',3'-cGAMP-C2-PPA (45) is a cyclic di-nucleotide that acts as a STING agonist (US20210015941A1) . It is a drug-linker conjugate for antibody-drug conjugates (ADC) used in the targeted treatment of cancer.

Smiles

[H][C@@]12COP(O)(=O)O[C@@]3([H])[C@@H](O)[C@@H](O[C@]3([H])COP(O)(=O)O[C@]([H])(C1CCSSC(C)CCC(O)=O)[C@@H](O2)n1cnc2c1[nH]c(N)nc2=O)n1cnc2c(N)ncnc12

Molecular Formula

C27H36N10O14P2S2

Molecular Weight

850.71

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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