QS11
Product Specifications
CAS Number
944328-88-5
Target
GTPase, Others, Wnt/beta-catenin
Related Pathways
Stem Cells, Cytoskeletal Signaling, GPCR/G Protein, Others
Purity
>99.99%
Bioactivity
QS11 is a GTPase activating protein of ADP-ribosylation factor 1 (ARFGAP1) inhibitor. Modulates ARF-GTP levels and synergizes with the Wnt/β-catenin signaling pathway to upregulate β-catenin nuclear translocation. Also reduces in vitro migration of metastatic human breast cancer cells.
Smiles
OC[C@H](Cc1ccccc1)Nc1nc(Oc2ccc3CCCc3c2)nc2n(Cc3ccc(cc3)-c3ccccc3)cnc12
Molecular Formula
C36H33N5O2
Molecular Weight
567.68
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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